PDGFRA (phospho Y574) Peptide
产品名称： PDGFRA (phospho Y574) Peptide
英文名称： PDGFRA (phospho Y574) Peptide
产品编号： P1482
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of PDGFRA.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y574 of human PDGFRA.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Dot Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- C/EBP is an essential component of PDGFRA transcription in MG-63 cells.
Afink G, Westermark UK, Lammerts E, Nister M.Biochem Biophys Res Commun. 2004 Mar 5;315(2):313-8.
- 2.
- Promoter haplotype combinations for the human PDGFRA gene are associated with risk of neural tube defects.
Zhu H, Wicker NJ, Volcik K, Zhang J, Shaw GM, Lammer EJ, Suarez L, Canfield M, Finnell RH.Mol Genet Metab. 2004 Feb;81(2):127-32.
- 3.
- The EOL-1 cell line as an in vitro model for the study of FIP1L1-PDGFRA-positive chronic eosinophilic leukemia.
Cools J, Quentmeier H, Huntly BJ, Marynen P, Griffin JD, Drexler HG, Gilliland DG.Blood. 2004 Apr 1;103(7):2802-5. Epub 2003 Nov 20.
- Entrez GeneID:
- 5156
- Protein Accession#:
- NP_006197;P16234
- Gene Name:
- PDGFRA
- Gene Alias:
- CD140A,MGC74795,PDGFR2,Rhe-PDGFRA
- Gene Description:
- platelet-derived growth factor receptor, alpha polypeptide
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. [provided by RefSeq
- Other Designations:
- FIP1L1/PDGFRA fusion protein,platelet-derived growth factor receptor alpha,rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein
- Related Disease