PSENEN (Human) Recombinant Protein (P01)
产品名称： PSENEN (Human) Recombinant Protein (P01)
英文名称： PSENEN (Human) Recombinant Protein (P01)
产品编号： H00055851-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human PSENEN full-length ORF ( AAH09575, 1 a.a. - 101 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MNLERVSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFFREAFLVPAYTEQSQIKGYVWRSAVGFLFWVIVLTSWITIFQIYRPRWGALGDYLSFTIPLGTP
- Theoretical MW (kDa):
- 36.85
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 55851
- GeneBank Accession#:
- BC009575
- Protein Accession#:
- AAH09575
- Gene Name:
- PSENEN
- Gene Alias:
- MDS033,MSTP064,PEN-2,PEN2
- Gene Description:
- presenilin enhancer 2 homolog (C. elegans)
- Omim ID:
- 607632
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. [provided by RefSeq
- Other Designations:
- hematopoietic stem/progenitor cells protein MDS033,presenilin enhancer 2
- Gene Pathway