FITC标记的DNA连接酶1抗体
产品名称： FITC标记的DNA连接酶1抗体
英文名称： Anti-DNA Ligase 1/FITC
产品编号： HZ-6641R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-DNA Ligase 1/FITC Conjugated antibody
FITC标记的DNA连接酶1抗体
| 英文名称 | Anti-DNA Ligase 1/FITC |
| 中文名称 | FITC标记的DNA连接酶1抗体 |
| 别 名 | DNA ligase 1; DNA ligase I; Polydeoxyribonucleotide synthase [ATP] 1; DNLI1_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 101kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DNA Ligase 1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Eukaryotic DNA ligases are ATP-dependent enzymes that catalyse the joining of single and double-strand DNA breaks, which is an essential final step in DNA replication, recombination and repair. Four biochemically distinct DNA ligases, termed ligases I-IV, have been identified in mammalian cells. DNA ligase I is functionally homologous to the DNA ligase encoded by the Saccharomyces cerevisiae Cdc9 gene. The joining of Okazaki fragments during lagging strand DNA replication in mammalian cells is due to DNA ligase I. Function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. Subcellular Location: Nucleus. Similarity: Belongs to the ATP-dependent DNA ligase family. Database links: UniProtKB/Swiss-Prot: P18858.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
真核DNA连接酶是ATP依赖性酶，催化单链和双链DNA断裂的结合，这是DNA复制、重组和修复过程中必不可少的最后一步。在哺乳动物细胞中已经鉴定出四种生物化学不同的DNA连接酶，称为连接酶i-IV。DNA连接酶Ⅰ与酿酒酵母CDC9基因编码的DNA连接酶具有同源性。Okaski片段在哺乳动物细胞中的滞后链DNA复制中的连接是由于DNA连接酶I。