UGT1A7 purified MaxPab mouse polyclonal antibody (B01P)
产品名称： UGT1A7 purified MaxPab mouse polyclonal antibody (B01P)
英文名称： UGT1A7 purified MaxPab mouse polyclonal antibody (B01P)
产品编号： H00054577-B01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human UGT1A7 protein.
- Immunogen:
- UGT1A7 (AAI53173.1, 1 a.a. ~ 530 a.a) full-length human protein.
- Sequence:
- MARAGWTGLLPLYVCLLLTCGFAKAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLGRSLNCTVKTYSTSYTLEDQDREFMVFADARWTAPLRSAFSLLTSSSNGIFDLFFSNCRSLFNDRKLVEYLKESCFDAVFLDPFDACGLIVAKYFSLPSVVFARGIFCHYLEEGAQCPAPLSYVPRLLLGFSDAMTFKERVWNHIMHLEEHLFCPYFFKNVLEIASEILQTPVTAYDLYSHTSIWLLRTDFVLEYPKPVMPNMIFIGGINCHQGKPVPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of UGT1A7 expression in transfected 293T cell line (H00054577-T01) by UGT1A7 MaxPab polyclonal antibody.
Lane 1: UGT1A7 transfected lysate(58.3 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 54577
- GeneBank Accession#:
- BC153172.1
- Protein Accession#:
- AAI53173.1
- Gene Name:
- UGT1A7
- Gene Alias:
- UDPGT,UGT1G
- Gene Description:
- UDP glucuronosyltransferase 1 family, polypeptide A7
- Omim ID:
- 606432
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has moderate glucuronidase activity with phenols. [provided by RefSeq
- Other Designations:
- OTTHUMP00000065057,UDP glycosyltransferase 1 family, polypeptide A6,UDP glycosyltransferase 1 family, polypeptide A7,UDP-glucuronosyltransferase 1 family polypeptide A7s,UDP-glucuronosyltransferase 1A7,UGT1A7*5 (Gly115Ser),UGT1A7*6 (Glu139Asp)
- Gene Pathway
- Androgen and estrogen metabolism
- Ascorbate and aldarate metabolism
- Drug metabolism - cytochrome P450
- Drug metabolism - other enzymes
- Metabolic pathways
- Metabolism of xenobiotics by cytochrome P450
- Pentose and glucuronate interconversions
- Porphyrin and chlorophyll metabolism
- Retinol metabolism
- Starch and sucrose metabolism
- Related Disease
- Adenocarcinoma
- Carcinoma, Hepatocellular
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Chronic Disease
- Cleft Lip
- Cleft Palate
- Colitis, Ulcerative
- Colon cancer
- Colonic Neoplasms
- Colorectal Neoplasms
- Crohn Disease
- Crohn's disease
- Diabetes Mellitus, Type 2
- Diarrhea
- DNA Damage
- Drug Toxicity
- Edema