HDAC4 (N-term) Peptide
产品名称: HDAC4 (N-term) Peptide
英文名称: HDAC4 (N-term) Peptide
产品编号: P0214
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of HDAC4.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human HDAC4.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Participation of histones and histone-modifying enzymes in cell functions through alterations in chromatin structure.
Nakayama T, Takami Y.J Biochem. 2001 Apr;129(4):491-9.
- 2.
- Histone deacetylase: a target for antiproliferative and antiprotozoal agents.
Meinke PT, Liberator P.Curr Med Chem. 2001 Feb;8(2):211-35.
- 3.
- Histone deacetylases, transcriptional control, and cancer.
Cress WD, Seto E.J Cell Physiol. 2000 Jul;184(1):1-16.
- Entrez GeneID:
- 9759
- Protein Accession#:
- P56524
- Gene Name:
- HDAC4
- Gene Alias:
- HA6116,HD4,HDAC-A,HDACA,KIAA0288
- Gene Description:
- histone deacetylase 4
- Omim ID:
- 605314
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq
- Other Designations:
- histone deacetylase A