CD63 monoclonal antibody, clone CLB-180
产品名称： CD63 monoclonal antibody, clone CLB-180
英文名称： CD63 monoclonal antibody, clone CLB-180
产品编号： MAB5246
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native CD63.
- Immunogen:
- Native purified CD63 from human cytochrome-B enriched cells.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- The monoclonal antibody is directed against the CD63-antigen, a 53 kD glycoprotein, which is expressed in platelet lysosomes, that are located to the platelet surface upon activation with strong agonists. The antigen is also present in most peripheral blood cells (not in erythrocytes cells) and in many tissues; both surface and cytoplasmic locations are reported.
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In 20 mM Tris, 150 mM NaCl, pH 8.0 (10 mg BSA, 0.001% thimerosal)
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Immunofluorescence
- Flow Cytometry
- Entrez GeneID:
- 967
- Gene Name:
- CD63
- Gene Alias:
- LAMP-3,ME491,MLA1,OMA81H,TSPAN30
- Gene Description:
- CD63 molecule
- Omim ID:
- 155740
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq
- Other Designations:
- CD63 antigen,CD63 antigen (melanoma 1 antigen),granulophysin,lysosome-associated membrane glycoprotein 3,melanoma 1 antigen,melanoma-associated antigen ME491,melanoma-associated antigen MLA1,ocular melanoma-associated antigen,tetraspanin-30
- Gene Pathway