FITC标记的RNA聚合酶II相关因子PAF1抗体
产品名称： FITC标记的RNA聚合酶II相关因子PAF1抗体
英文名称： Anti-PAF1/FITC
产品编号： HZ-21001R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-PAF1/FITC Conjugated antibody
FITC标记的RNA聚合酶II相关因子PAF1抗体
| 英文名称 | Anti-PAF1/FITC |
| 中文名称 | FITC标记的RNA聚合酶II相关因子PAF1抗体 |
| 别 名 | F23149 1; FLJ11123; hPAF1; PAF 1; PAF1; Paf1 RNA polymerase II associated factor homolog; PAF1_HUMAN; Pancreatic differentiation protein 2; PD 2; PD2; PD2 protein; RNA polymerase II associated factor homolog; RNA polymerase II-associated factor 1 homolog. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 60kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PAF1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a subunit of the polymerase associated factor (PAF1) complex. The PAF1 complex interacts with RNA polymerase II and plays a role in transcription elongation as well as histone modifications including ubiquitylation and methylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012] Function: The mammalian PAF1 complex is a multifunctional complex. The PAF1 complex interacts with RNA polymerase II and may be involved in both initiation and elongation, and in histone methylation and RNA processing. Has oncogenic activity in vivo and in vitro. Subcellular Location: Nucleus. Punctuate distribution throughout the nucleus except in nucleoli and the perinuclear chromatin. Similarity: Belongs to the PAF1 family. Database links: Entrez Gene: 54623 Human Entrez Gene: 54624 Mouse Entrez Gene: 361531 Rat Entrez Gene: 446278 Xenopus laevis Omim: 610506 Human SwissProt: Q8N7H5 Human SwissProt: Q8K2T8 Mouse SwissProt: Q4V886 Rat SwissProt: A2BD83 Xenopus laevis Unigene: 466714 Human Unigene: 7916 Mouse Unigene: 161558 Rat Unigene: 29705 Xenopus laevis Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码聚合酶相关因子（PAF1）复合物的亚基。PAF1复合物与RNA聚合酶II相互作用，在转录延长以及组蛋白修饰（包括泛素化和甲基化）中发挥作用。另一种编码多个异构体的剪接转录变体已被观察到该基因。[ RefSeq，FEB 2012 ]提供