FITC标记的肝肠钙粘连蛋白抗体
产品名称： FITC标记的肝肠钙粘连蛋白抗体
英文名称： Anti-LI Cadherin/FITC
产品编号： HZ-1617R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-LI Cadherin/FITC Conjugated antibody
FITC标记的肝肠钙粘连蛋白抗体
| 英文名称 | Anti-LI Cadherin/FITC |
| 中文名称 | FITC标记的肝肠钙粘连蛋白抗体 |
| 别 名 | BILL-cadherin; LI-cadherin; CAD17_HUMAN; Cadherin 16; Cadherin 16, formerly; Cadherin 17; cadherin 17, LI cadherin (liver-intestine); cadherin, liver-intestine; Cadherin-17; CDH16; CDH16, formerly; Cdh17; FLJ26931; Formerly Cadherin 16; Formerly CDH16; HPT 1; HPT-1 cadherin; human intestinal peptide-associated transporter HPT-1; human peptide transporter 1; Intestinal peptide-associated transporter HPT 1; Intestinal peptide-associated transporter HPT-1; LI-cadherin; Liver Cadherin; liver intestine cadherin; Liver-intestine cadherin. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 免疫学 细胞骨架 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 90kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LI-cadherin |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. Subcellular Location: Cell membrane; Single-pass type I membrane protein (Potential). Tissue Specificity: Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. Similarity: Contains 7 cadherin domains. Database links: Entrez Gene: 1015 Human Omim: 603017 Human SwissProt: Q12864 Human Unigene: 591853 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 肝肠钙粘连蛋白是钙粘连蛋白超家族中的特殊一员,在结构上与经典Ⅰ型钙粘连蛋白有所不同而被划分为经典钙粘连蛋白的变异体，主要用于消化道肿瘤方面的研究 |
该基因是钙粘蛋白超家族的成员，编码钙依赖的膜相关糖蛋白基因。该编码蛋白是钙粘蛋白样蛋白，由细胞外区组成，包含7个钙粘蛋白结构域，以及一个跨膜区，但缺乏保守的细胞质结构域。该蛋白是胃肠道和胰管的组成部分，在许多医学上重要的肽类药物的口服吸收的第一步中作为肠质子依赖性肽转运体。蛋白质也可能在肝脏和肠道的形态组织中起作用。选择性剪接导致多个转录变体。