ARVCF monoclonal antibody (M01), clone 5D2
产品名称： ARVCF monoclonal antibody (M01), clone 5D2
英文名称： ARVCF monoclonal antibody (M01), clone 5D2
产品编号： H00000421-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant ARVCF.
- Immunogen:
- ARVCF (NP_001661, 863 a.a. ~ 962 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- LSPGGFDDSTLPLVDKSLEGEKTGSRDVIPMDALGPDGYSTVDRRERRPRGASSAGEASEKEPLKLDPSRKAPPPGPSRPAVRLVDAVGDAKPQPVDSWV
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Xenopus Kazrin interacts with ARVCF-catenin, spectrin and p190B RhoGAP, and modulates RhoA activity and epithelial integrity.
Cho K, Vaught TG, Ji H, Gu D, Papasakelariou-Yared C, Horstmann N, Jennings JM, Lee M, Sevilla LM, Kloc M, Reynolds AB, Watt FM, Brennan RG, Kowalczyk AP, McCrea PD.J Cell Sci. 2010 Dec 1;123(Pt 23):4128-44. Epub 2010 Nov 9.
- Applications
- Western Blot (Cell lysate)
- ARVCF monoclonal antibody (M01), clone 5D2 Western Blot analysis of ARVCF expression in A-431 ( Cat # L015V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to ARVCF on formalin-fixed paraffin-embedded human stomach. [antibody concentration 3 ug/ml]
- Protocol Download
- Entrez GeneID:
- 421
- GeneBank Accession#:
- NM_001670
- Protein Accession#:
- NP_001661
- Gene Name:
- ARVCF
- Gene Alias:
- FLJ35345
- Gene Description:
- armadillo repeat gene deletes in velocardiofacial syndrome
- Omim ID:
- 602269
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family which play an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS) a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein. [provided by RefSeq
- Other Designations:
- armadillo repeat protein
- Related Disease
- Anorexia Nervosa
- Cerebral Hemorrhage
- Chronic Disease
- Cleft Lip
- Cleft Palate
- Genetic Predisposition to Disease
- Hypertension
- Intracranial Hemorrhages
- Kidney Diseases
- Kidney Failure, Chronic
- Psychotic Disorders
- Schizophrenia
- Schizophrenia
- Stroke
- Subarachnoid Hemorrhage
- Tobacco Use Disorder
- Urinary Bladder Neoplasms