CRK polyclonal antibody
产品名称： CRK polyclonal antibody
英文名称： CRK polyclonal antibody
产品编号： PAB18119
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CRK.
- Immunogen:
- A synthetic peptide corresponding to human CRK.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- This antibody is specific to CRK.
- Form:
- Liquid
- Purification:
- Affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Anabolic effects of a G protein-coupled receptor kinase inhibitor expressed in osteoblasts.
Spurney RF, Flannery PJ, Garner SC, Athirakul K, Liu S, Guilak F, Quarles LD.J Clin Invest. 2002 May;109(10):1361-71.
- 2.
- Isolation of Trypanosoma brucei CYC2 and CYC3 cyclin genes by rescue of a yeast G(1) cyclin mutant. Functional characterization of CYC2.
Van Hellemond JJ, Neuville P, Schwarz RT, Matthews KR, Mottram JC.J Biol Chem. 2000 Mar 24;275(12):8315-23.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of extracts from COS-7 cells, using CRK polyclonal antibody (Cat # PAB18119).
Peptide "+" means "peptide blocking".
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using CRK polyclonal antibody (Cat # PAB18119).
Peptide "+" means "peptide blocking".
- Entrez GeneID:
- 1398
- Protein Accession#:
- P46108
- Gene Name:
- CRK
- Gene Alias:
- CRKII
- Gene Description:
- v-crk sarcoma virus CT10 oncogene homolog (avian)
- Omim ID:
- 164762
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq
- Other Designations:
- avian sarcoma virus CT10 (v-crk) oncogene homolog,v-crk avian sarcoma virus CT10 oncogene homolog,v-crk sarcoma virus CT10 oncogene homolog
- Interactome
