美国PeproTech公司是全球最大的重组细胞因子和蛋白生产商之一，始终致力于为生命科学研究开发重组蛋白及相关产品，如今已成为能提供多种高质量细胞因子和重组蛋白，相应的单克隆、多克隆和生物素标记抗体，以及ELISA试剂盒的引领者。PeproTech.的产品涵盖免疫调节蛋白、白介素、集落刺激因子、生长因子、无动物成分的重组蛋白、化学趋化因子、干扰素、脂联素、成纤维生长因子、转化生长因子、肿瘤坏死因子、神经营养素和防御素等诸多生命科学研究领域中重要的生物活性分子。PeproTech公司的产品种类、规格齐全，更新速度快，且价格适中，已广为中国的科研工作者所使用。
| 为跟踪当今科研发展、满足日益增长的需求，PeproTech公司追求不断创新和与时俱进。PeproTech公司2019年9月推出4种新产品，分别是：| 类别 | 名称 | 货号 | 规格 | 价格/RMB | | 细胞因子 | Murine C5a | 315-40 | 5ug | ￥1,050 | | 细胞因子 | Murine C5a | 315-40 | 20ug | ￥2,570 | | 细胞因子 | Murine C5a | 315-40 | 100ug | ￥9,240 | | 细胞因子 | Murine C5a | 315-40 | 250ug | ￥16,170 | | 细胞因子 | Murine C5a | 315-40 | 500ug | ￥27,720 | | 细胞因子 | Murine C5a | 315-40 | 1000ug | ￥46,200 | | 细胞因子 | Murine TARC (CCL17) | 250-43 | 5ug | ￥1,050 | | 细胞因子 | Murine TARC (CCL17) | 250-43 | 20ug | ￥2,570 | | 细胞因子 | Murine TARC (CCL17) | 250-43 | 100ug | ￥9,240 | | 细胞因子 | Murine TARC (CCL17) | 250-43 | 250ug | ￥16,170 | | 细胞因子 | Murine TARC (CCL17) | 250-43 | 500ug | ￥27,720 | | 细胞因子 | Murine TARC (CCL17) | 250-43 | 1000ug | ￥46,200 | | 细胞因子 | Murine KGF (FGF-7) | 450-60 | 2ug | ￥1,050 | | 细胞因子 | Murine KGF (FGF-7) | 450-60 | 10ug | ￥2,570 | | 细胞因子 | Murine KGF (FGF-7) | 450-60 | 50ug | ￥9,600 | | 细胞因子 | Murine KGF (FGF-7) | 450-60 | 100ug | ￥16,010 | | 细胞因子 | Murine KGF (FGF-7) | 450-60 | 250ug | ￥28,020 | | 细胞因子 | Murine KGF (FGF-7) | 450-60 | 500ug | ￥48,040 | | 细胞因子 | Murine KGF (FGF-7) | 450-60 | 1000ug | ￥80,080 | | 无动物成分细胞因子 | Human 4-1BB Ligand | AF-310-11 | 5ug | ￥1,250 | | 无动物成分细胞因子 | Human 4-1BB Ligand | AF-310-11 | 20ug | ￥2,830 | | 无动物成分细胞因子 | Human 4-1BB Ligand | AF-310-11 | 100ug | ￥10,160 | | 无动物成分细胞因子 | Human 4-1BB Ligand | AF-310-11 | 250ug | ￥17,780 | | 无动物成分细胞因子 | Human 4-1BB Ligand | AF-310-11 | 500ug | ￥30,490 | | 无动物成分细胞因子 | Human 4-1BB Ligand | AF-310-11 | 1000ug | ￥50,820 |
1.重组小鼠C5a
产品描述:Complement 5a (C5a) is an enzymatically generated glycoprotein belonging to the anaphylatoxin family of structurally and functionally related proteins. Generated upon the activation of the complement system, C5a, together with C4a, C3a, and the membrane attack complex (C5b‐9), functions as a central player in host defense by inducing smooth muscle cell contraction, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes through cell degranulation. In addition to acting as a direct mediator of localized inflammatory response, C5a also initiates both the synthesis and release of IL‐8 from monocytes and bronchial epithelial cells, stimulates the proliferation of neurons and hepatocytes, and functions as a potent chemoattractant. Where C5a deficiency, a rare defect of the complement pathway caused by the mutation of the C5a gene, is associated with susceptibility to severe infections, excessive C5a activation has been linked to liver fibrosis, sepsis, adult respiratory distress syndrome, rheumatoid arthritis, Alzheimer’s disease, and ischemic heart disease. Human C5a shares 60% and 54% sequence identity to mouse and rat C5a, respectively. The human C5 gene encodes a 1,676 amino acid glycoprotein that is comprised of a disulfide‐linked C5 alpha and a C5 beta chain, the former of which contains the active, 74 amino acid C5a anaphylatoxin chain. Recombinant Murine C5a is an 8.9 kDa glycoprotein containing the 77 amino acid residues of the C5a anaphylatoxin chain.
2.重组小鼠TARC (CCL17)
产品描述:TARC, a CC chemokine, is predominantly produced by dendritic cells in the thymus, and signals through the CCR4 receptor. TARC is chemotactic towards T cells. Recombinant Murine TARC (CCL17) is an 7.9 kDa protein containing 70 amino acid residues, including the four conserved cysteine residues present in CC chemokines.
3.重组小鼠KGF (FGF-7)
产品描述:KGF (FGF‐7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. KGF (FGF‐7) is a mitogen factor specific for epithelial cells and keratinocytes. KGF/FGF‐7 signals through FGFR 2b. KGF (FGF‐7) plays a role in kidney and lung development, as well as in angiogenesis and wound healing. Recombinant Murine KGF (FGF‐7) is an 18.9 kDa protein consisting of 164 amino acid residues.
4.无动物成份重组人4-1BB Ligand
产品描述:4‐1BBL, a member of the TNF superfamily, is expressed in B cells, dendritic cells, activated T cells and
macrophages. 4‐1BBL binds to its receptor 4‐1BB, and provides a co‐stimulatory signal for T cell activation and expansion. The human 4‐1BBL gene codes for a 254 amino acid type II transmembrane protein containing a 28 amino acid cytoplasmic domain, a 21 amino acid transmembrane protein domain, and a 205 amino acid extracellular domain. The soluble form of 4‐1BBL contains the TNF‐like portion of the extracellular domain of 4‐1BBL. Recombinant Human 4‐1BB Ligand is a soluble 19.5 kDa protein consisting of 185 amino acid residues. | |
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